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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MFSD6
All Species:
20.91
Human Site:
T246
Identified Species:
41.82
UniProt:
Q6ZSS7
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZSS7
NP_060164.3
791
88088
T246
D
L
T
L
N
S
S
T
A
T
P
V
S
P
G
Chimpanzee
Pan troglodytes
XP_001166645
791
87868
T246
D
L
T
L
N
S
S
T
A
T
P
V
S
P
G
Rhesus Macaque
Macaca mulatta
XP_001108155
793
88202
T247
D
L
T
L
N
S
S
T
A
T
P
V
V
P
P
Dog
Lupus familis
XP_545567
795
87768
S247
G
H
G
R
D
F
T
S
S
P
S
P
A
A
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8CBH5
775
86057
T249
G
L
I
L
N
T
S
T
V
T
L
P
P
T
G
Rat
Rattus norvegicus
NP_001100381
794
87984
T249
D
L
I
L
N
T
S
T
V
T
L
P
P
T
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521818
279
29754
Chicken
Gallus gallus
XP_421837
786
86648
T250
T
H
F
L
L
K
N
T
T
V
T
T
S
P
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q1LUQ4
793
88213
T264
S
T
S
I
S
T
S
T
P
S
S
T
N
T
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610983
762
83293
T237
Q
E
H
L
D
M
G
T
G
T
M
P
A
D
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_498662
630
68991
P129
T
C
Q
T
M
L
A
P
A
G
K
I
I
R
G
Sea Urchin
Strong. purpuratus
XP_787405
722
79257
P222
K
S
I
G
T
E
E
P
I
R
R
L
P
S
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
98.1
87.3
N.A.
83.8
87.9
N.A.
26.1
77.5
N.A.
56.1
N.A.
35.5
N.A.
27
23.7
Protein Similarity:
100
99.4
98.6
91
N.A.
88.6
91.4
N.A.
29.3
84.4
N.A.
71.2
N.A.
52.2
N.A.
44.5
40.7
P-Site Identity:
100
100
86.6
0
N.A.
46.6
53.3
N.A.
0
33.3
N.A.
13.3
N.A.
20
N.A.
13.3
6.6
P-Site Similarity:
100
100
86.6
33.3
N.A.
53.3
60
N.A.
0
40
N.A.
53.3
N.A.
33.3
N.A.
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
9
0
34
0
0
0
17
9
0
% A
% Cys:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
34
0
0
0
17
0
0
0
0
0
0
0
0
9
0
% D
% Glu:
0
9
0
0
0
9
9
0
0
0
0
0
0
0
9
% E
% Phe:
0
0
9
0
0
9
0
0
0
0
0
0
0
0
0
% F
% Gly:
17
0
9
9
0
0
9
0
9
9
0
0
0
0
59
% G
% His:
0
17
9
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
25
9
0
0
0
0
9
0
0
9
9
0
0
% I
% Lys:
9
0
0
0
0
9
0
0
0
0
9
0
0
0
0
% K
% Leu:
0
42
0
59
9
9
0
0
0
0
17
9
0
0
0
% L
% Met:
0
0
0
0
9
9
0
0
0
0
9
0
0
0
0
% M
% Asn:
0
0
0
0
42
0
9
0
0
0
0
0
9
0
0
% N
% Pro:
0
0
0
0
0
0
0
17
9
9
25
34
25
34
17
% P
% Gln:
9
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
9
0
0
0
0
0
9
9
0
0
9
0
% R
% Ser:
9
9
9
0
9
25
50
9
9
9
17
0
25
9
0
% S
% Thr:
17
9
25
9
9
25
9
67
9
50
9
17
0
25
9
% T
% Val:
0
0
0
0
0
0
0
0
17
9
0
25
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _